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What Are Psychedelic Drugs Hallucinogenics? Their findings were consistent with the observation of a dense band of 5-HT2 receptors in upper cortical layer V in register with a dense plexus of fine 5-HT axons (Blue et al., 1988). A mRNA in situ hybridization study of human cortex demonstrated the 5-HT2A receptor on both pyramidal and nonpyramidal cells (Burnet et al., 1995). In a subsequent study, it was found that Sr2+ fully substituted for Ca+2 in supporting the 5-HT–induced increase in spontaneous EPSC frequency, but only partially with respect to amplitude . In the presence of Sr2+, however, late asynchronous evoked EPSPs followed each electrical stimulus, with an absence of synchronous EPSCs. Psychedelic microdosing is the practice of using sub-threshold doses of psychedelics in an attempt to improve creativity, boost physical energy level, emotional balance, increase performance on problems-solving tasks and to treat anxiety, depression and addiction. The practice of microdosin